The actress, who was famously comfortable with nudity, was also a fierce advocate for people with AIDS, prisoners and the homeless.
Sally Kirkland, a former model and Oscar nominated actress known for her roles in films such as Anna, The Sting and JFK has died aged 84.
Her representative, Michael Greene, said Kirkland died on Tuesday morning at a Palm Springs hospice.
Kirkland had been unwell and struggling to cover medical bills after she fractured six bones last year and developed two life-threatening infections. She had also been diagnosed with dementia.
A GoFundMePage that was set up by her friends to help pay for her ongoing treatment had raised over £45,000 ($60,000).
