Домой United States USA — Science AstraZeneca’s ‘mistake’ in COVID-19 vaccine trials could halt approval

AstraZeneca’s ‘mistake’ in COVID-19 vaccine trials could halt approval

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Maybe not such a “happy” accident after all.
AstraZeneca’s coronavirus vaccine is coming under intense scrutiny after its UK scientists made a major “mistake” during …

Maybe not such a “happy” accident after all. AstraZeneca’s coronavirus vaccine is coming under intense scrutiny after its UK scientists made a major “mistake” during trials — one that could even halt it from getting approved, according to reports. The UK drugmaker and its partner, Oxford University, admitted — after reporting its vaccine tested up to 90 percent effective — that the promising results came after a batch of volunteers were accidentally given half doses. The efficacy of the vaccine was significantly lower at 62 percent for those who received the correctly administered two full doses. Lead researcher Mene Pangalos insisted it was “serendipity,” but the error, which was not reported in the initial findings, has brought the vaccine under intense scrutiny from scientists and industry experts. The half-dose group was just 2,741 volunteers — and all were under 55, raising questions as to whether the relative youth of the participants created the positive results, not the size of the dose. “It pains me to say this, but… I think the claims made for the Oxford/AstraZeneca Covid-19 vaccine are on *very* shaky ground.

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