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Orioles vs. Red Sox prediction: MLB Opening Day picks, odds Thursday

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We have an Orioles vs. Red Sox prediction as Major League Baseball begins in Boston and the American League East. 
The Orioles and Red Sox are the main divisional competitors for last place. 
The Yankees, Blue Jays, and Rays all have reasonable betting odds of winning the AL East, while Baltimore and Boston sit closer to 30-to-1. 
Two cast-off starting pitchers, Kyle Gibson and Corey Kluber, will share the mound, speaking to how low the expectations are for both squads in 2023. 
Then again, both teams should be fun watches this season. Baltimore and Boston combine poor pitching staffs with electric, high-upside lineups, so we should see high-scoring baseball games. 
But before we keep dragging the Orioles and Red Sox through the mud, let’s dive into the odds and my prediction and pick for the game. Orioles vs. Red Sox odds
Moneyline: Orioles (+110) vs. Red Sox (-130)
Spread: Orioles +1.5 (-184) vs. Red Sox -1.5 (+152)
Total: Over 9 (-115) | Under 9 (-105) Orioles vs. Red Sox prediction
(2:10 p.m. ET.)
Both lineups have a high upside, but the Red Sox and Orioles are trying to emphasize different strengths behind the plate.

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