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Bills vs. Bears prediction: NFL Week 16 picks, odds

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The Buffalo Bills travel to Chicago to face the Bears on Christmas Eve. The Bills are a hefty road favorite in this matchup, with the total just north of 40. 
The total is what stands out to me. This number feels a little low for the 2022 edition of the Chicago Bears. The Bears had gone over in seven consecutive games until last week versus the Eagles. However, that’s because the number was 48. The two teams scored a combined 45 points.

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