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Buffalo Bills at Chicago Bears: Predictions, picks and odds for NFL Week 16 matchup

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The Buffalo Bills (11-3) punched their ticket into the playoffs last week, but they still have the AFC East title to play for. Quarterback Josh Allen is in MVP contention and is seeking to show voters that he’s a more valuable player than Patrick Mahomes and Jalen Hurts.
The Chicago Bears (3-11) have been eliminated from playoff contention and can start looking to next year. But quarterback Justin Fields still has reason to perform as he’s chasing the single-season record for rushing yards by a quarterback.
Here’s a look at the betting details and USA TODAY’s NFL staff picks for the Bills vs. Bears Week 16 game:
Spread: Bills (-8.5)
Moneyline: Bills (-400); Bears (+325)
Over/under: 40.5
More odds, injury info for Bills at Bears
COOL MOMENT:Bills WR Stefon Diggs surprised young fan with custom Nikes in emotional exchange
DRIP CHECK:Stefon Diggs rocks a luxe balaclava; Jerry Jeudy bundles up
PLAYOFF PICTURE:Chiefs wrap up AFC West, Giants clinch spot for Cowboys
Jaguars at Jets | Falcons at Ravens | Lions at Panthers | Bills at Bears | Saints at Browns | Seahawks at Chiefs | Giants at Vikings | Bengals at Patriots | Texans at Titans | Commanders at 49ers | Eagles at Cowboys | Raiders at Steelers | Packers at Dolphins | Broncos at Rams | Buccaneers at Cardinals | Chargers at Colts
Chicago gave Philadelphia a stiff challenge last week at home, and they’ll do the same to Buffalo.

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