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College football Week 6 betting trends: Odds ATS, tips, stats

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All of the betting nuggets, trends, stats and information ahead of Week 6 of the college football season.
Week 6 of the college football season features more teams around the country starting their conference schedule, including three matchups between ranked teams in the AP Top 25.
Hendon Hooker and the No. 8 Tennessee Volunteers kick things off with an SEC matchup with the No. 25 LSU Tigers, while No. 17 TCU, fresh off an upset victory over Oklahoma, takes on undefeated No. 19 Kansas in Lawrence. The final ranked matchup of the weekend is a Pac-12 showdown between No. 11 Utah and No. 18 UCLA. Chip Kelly’s Bruins might be a surprising contender in the conference after defeating Washington on Friday.
But which games should bettors look at across this weekend’s slate?
We have everything you need to make your wagering decisions ahead of Week 6.
Check out all of the betting notes and trends courtesy of ESPN Stats & Information.
No. 4 Michigan at Indiana (-22, 59)
12 p.m. ET, Memorial Stadium, Bloomington, Indiana
Indiana is 0-6 ATS and SU against ranked opponents since the start of last season.
Michigan is 12-4 ATS as a favorite since the start of last season, and 4-1 ATS as a road favorite over the same span.
Michigan is 9-3 ATS since the start of last season as a double-digit favorite since the start of 2021, tied with Georgia for the 2nd-most covers as a double-digit favorite in that span (ALA- 11).
Indiana is 2-9 ATS in Big Ten games since the start of the 2021 season.
No. 8 Tennessee (-2.5, 64) at No. 25 LSU
12 p.m. ET on ESPN, Tiger Stadium, Baton Rouge, Louisiana
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LSU is 3-0 ATS at home this season, and 4-0-1 ATS in their last five games as a home underdog.
Four of LSU’s five games this season have gone to the under.
LSU is 3-1 ATS against AP Top-10 teams in the last two seasons.
Tennessee is 3-0 ATS in their last 3 games as a road favorite, but 0-3 ATS in their last three conference games.
No. 17 TCU (-7, 67.5) at No. 19 Kansas
12 p.m. ET, David Booth Kansas Memorial Stadium, Lawrence
Kansas is one of five FBS teams that are 5-0 ATS this season.
Kansas opened the season +30000 to win the Big 12, the longest odds of any team. With their 5-0 start to the season, they’ve jumped to +1200, 6th-shortest in the conference.
TCU is 3-0 ATS as a favorite so far this season, while Kansas is 3-0 ATS as an underdog.
TCU’s last four games against ranked opponents have all gone to the over.
Arkansas at No. 23 Mississippi State (-8, 62)
12 p.m. ET on SEC Network, Davis Wade Stadium, Starkville, Mississippi
Arkansas is 10-4-1 ATS in their last 15 games against AP ranked opponents.
Arkansas is 7-2-1 ATS in their last 10 road games.
11 of the last 15 meetings between these two teams have gone to the over.
The last time Mississippi State played a game as a ranked team came in 2020 week 5 against Arkansas. MSST was favored by 17 points and failed to cover.
Texas at Oklahoma (-7, 65)
12 p.m. ET on ABC, Cotton Bowl, Dallas
Texas is 4-1 ATS in their last five games as a favorite.
Oklahoma has brought the offense following losses, with 16 games going to the over and just three to the under in games following a loss since the start of the 2012 season.

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