Ms Wiles, 67, is the daughter of the late American footballer Pat Summerall. She grew up in New Jersey and has worked for several prominent Republicans in both Florida and at the White House.
Donald Trump has named Susie Wiles as his White House chief of staff in his first major appointment as president-elect.
She will be the first female in history to take up the role – one of the most important non-elected posts in Washington.
In his victory speech, Mr Trump described her as an « ice maiden » and has credited her with his « best-run » campaign.
Here’s what we know about her so far.
Daughter of American footballer
Susie Wiles grew up in New Jersey. Her father was the late American footballer Pat Summerall.
Before his death in 2013, he credited her with helping him get sober and checking in to an alcohol rehab programme.
« I hadn’t been there much for my kids », he wrote in his memoir. « But Susan’s letter made it clear that I’d hurt them even in my absence. »
Ms Wiles’s first job in politics was in the 1970s as an assistant to the late Jack Kemp, who became a Republican representative for New York after playing alongside her father at the New York Giants.
The now 67-year-old was later part of Ronald Reagan’s presidential campaign and subsequently worked as a White House scheduler during his term.