A consortium of researchers with multidisciplinary skills, coordinated by INRAE and including the CNRS, the Université Paris-Saclay and Inserm, has identified a molecule capable of « disarming » pathogenic bacteria in the face of the immune system, without any negative effects on the host microbiota, promising a new strategy to combat antibiotic resistance.
A consortium of researchers with multidisciplinary skills, coordinated by INRAE and including the CNRS, the Université Paris-Saclay and Inserm, has identified a molecule capable of « disarming » pathogenic bacteria in the face of the immune system, without any negative effects on the host microbiota, promising a new strategy to combat antibiotic resistance.
These results, already patented and recently published in Nature Communications, are leading to the development of new drugs.
Antibiotic resistance is a major public health issue. According to the WHO, 5 million people die every year worldwide as a result of antibiotic resistance. This could become the leading cause of death by 2050.
Although antibiotics have considerably reduced the mortality associated with infectious diseases, their sometimes excessive and abusive use has led to the development of bacterial resistance.
