The Clippers control the game for more than three quarters, but Tyrese Maxey (39 points) and Philadelphia surge ahead in the fourth and hang on to hand the Clippers their eighth loss in the past nine games, 110-108.
James Harden and the short-handed Clippers found themselves on the wrong end of another tight game.
Harden scored 28 points and logged another career milestone on Monday night, but the Clippers squandered a 10-point fourth-quarter lead and lost to the Philadelphia 76ers, 110-108, coming up short at the final buzzer for the second time in as many days.
Tyrese Maxey scored 39 points and Paul George had nine points and seven rebounds in his season debut to lead the 76ers. Quentin Grimes added 19 points and Andre Drummond had 14 points and 18 rebounds while filling in for Joel Embiid. Rookie VJ Edgecombe added 14 points.
Harden became the 11th NBA player to eclipse 28,000 career points with a first-quarter layup but misfired on two 3-point attempts in the final seconds as the Clippers lost for the eighth time in nine games. Harden missed a potential game-tying 3-point shot at the buzzer in their 121-118 loss in Boston on Sunday afternoon.
Harden, who has been logging hefty minutes while carrying the team of late, shot 7 for 25 from the field (2 for 12 from 3-point range) on Monday, but he made all 12 of his free throws to go with six rebounds, five assists (with four turnovers) and two blocked shots in 28 minutes.