The missile strike left staff and children dead at the medical facility, says Save the Children.
A charity has condemned an air strike near a hospital in rebel-held north-western Yemen that killed at least eight people, five of them children.
A missile hit a petrol station 50m (164ft) from the entrance of the Kitaf rural hospital on Tuesday morning, according to Save the Children.
The blast also injured eight people.
It was not clear who was behind the attack, but a Saudi-led coalition is carrying out air strikes in support of the government in Yemen’s civil war.
The coalition insists it never deliberately targets civilians, but human rights groups have accused it of bombing markets, schools, hospitals and residential areas.
Tuesday was the fourth anniversary of the escalation of the civil war, which has killed thousands and pushed millions to the brink of starvation. What happened in Kitaf?
Save the Children says the petrol station in the area, which is 60km (40 miles) from the city of Saada, was struck by a missile at about 09:30 (06:30 GMT) on Tuesday, as many people were arriving at the nearby hospital.
An eight-year-old boy was the youngest person killed. Another boy aged 10, two boys aged 12, and one boy aged 14 also lost their lives.
One injured health worker, who was in the emergency room treating two young children when the strike happened, said: « All people were screaming and running out of the hospital.
